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KRINTAFEL (tafenoquine) is an 8-aminoquinoline antimalarial that inhibits parasite growth by interfering with the electron transport chain in the mitochondria of Plasmodium species It is active against both the erythrocytic and exoerythrocytic stages, including hypnozoites of P vivax Nov 10, 2025 · Krintafel side effects Get emergency medical help if you have signs of an allergic reaction: hives; dizziness, difficult breathing; swelling of your face, lips, tongue, or throat Krintafel may cause serious side effects Call your doctor at once if you have: pale or yellowed skin, dark colored urine; darkening of your mouth, lips, or fingernails; fast heartbeats, shortness of breath; a Generic name: tafenoquine succinate KRINTAFEL is an antimalarial indicated for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged 16 years and older who are receiving chloroquine therapy for acute P vivax infection (1) Limitations of Use Get label info, coverage requirements, PA forms & patient materials for Krintafel (tafenoquine succinate) Current, verified resources, all in one place Krintafel (tafenoquine succinate) tablet, film coated GlaxoSmithKline LLC 1 INDICATIONS AND USAGE KRINTAFEL is indicated for the radical cure (prevention of relapse) of Plasmodium vivax malaria in patients aged 16 years and older who are receiving chloroquine therapy for acute P vivax infection [see Dosage and Administration (2 2 See full list on drugs com Jul 20, 2018 · About Krintafel (tafenoquine) Krintafel is an 8-aminoquinoline derivative with activity against all stages of the P vivax lifecycle, including hypnozoites It was first synthesised by scientists at the Walter Reed Army Institute of Research in 1978 Package insert product label Dosage form: tablet, film coated Drug class: Antimalarial quinolines
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